Endocrine Abstracts

Background: Adrenocortical carcinomas (ACC) are rare aggressive tumors occurring at a rate of less than two per million per year. Uncommonly, there can be intravascular extension into renal veins and inferior vena cava (IVC), with resultant poorer prognosis.Clinical Case: A 26-year-old woman was referred for investigation of a two-month history of persistent left-sided abdominal pain - Computed tomography (CT) revealed a heterogeneous 12 cm left adrenal ...

Introduction: The short synacthen test (SST) is used in clinical practice to assess adrenal insufficiency (AI). However, the suggested threshold varies according to the patient cohort studied, assay variation and prevalence of the condition relative to the size of population tested. This study aimed to identify a threshold cortisol value to determine adrenal sufficiency in a Southeast Asian population and to investigate the utility of a stimulated 60-minute cortisol level in t...

Background: The Short Synacthen test (SST) is commonly used in clinical practice to evaluate adrenal function. Appropriate patient selection for SST is needed to ensure accurate interpretation of the results and to mitigate increased healthcare costs associated with unnecessary testing and inappropriate glucocorticoid (GC) steroid replacement. This study aimed to investigate the indications of inpatient SSTs over a one-year period, to determine the accuracy of testing.<p c...